Summary and Implications
Two related advanced intercross lines were analyzed for association of Gallinacin genotypic variation with Salmonella enteritidis (SE) burden levels in the spleen and cecum. Four Gallinacin genes were associated with bacterial load in the cecal content (GAL3, GAL11, GAL12, and GAL13) and one gene with SE bacterial burden in the spleen (GAL5). These results strongly support a role of the Gallinacins as defense molecules against enteric pathogens.
Iowa State University
Hasenstein, Jason and Lamont, Susan J.
"Chicken Gallinacin Gene Cluster Associated with Salmonella
Colonization in Two Advanced Intercross Lines,"
Animal Industry Report:
AS 653, ASL R2215.
Available at: http://lib.dr.iastate.edu/ans_air/vol653/iss1/41