Summary and Implications
Twenty-five multiparous Holstein cows were grouped according to infection status with Mycobacterium avium subsp. paratuberculosis (MAP), the causative microorganism of Johne’s disease (JD). Osteopontin (Opn) was characterized at both the level of gene and protein expression. Results of this study indicate that in dairy cows, expression of Opn is modulated by natural infection with MAP and by the periparturient period.
Iowa State University
Karcher, Elizabeth L.; Beitz, Donald C.; and Stabel, Judith R.
"Osteopontin Expression in Periparturient Dairy Cows Naturally
Infected with Mycobacterium Avium Subsp. Paratuberculosis,"
Animal Industry Report:
AS 654, ASL R2305.
Available at: http://lib.dr.iastate.edu/ans_air/vol654/iss1/54