Summary and Implications
A 3,072 single nucleotide polymorphism (SNP) panel was used to identify genetic markers linked to quantitative trait loci (QTL). Two association methods were used to search for QTL, SNP-wise and genome-wise models. The QTL associated with SNPs, found using both of these methods, can be applied to breeding programs in marker assisted selection (MAS).
The extent and consistency of linkage disequilibrium (LD) was measured in two lines of commercial egg laying chickens by analysis of SNPs. Correlations were drawn between measurements of two consecutive years to determine consistency. At short distances, LD is retained which allows for markers at high LD with a trait to be effectively applied in MAS.
Iowa State University
Beach, Erin; Abasht, Behnam; Fernando, Rohan L.; Dekkers, Jack C.M.; Lamont, Susan J.; Arango, Jesus; Settar, Petek; Fulton, Janet; and O'Sullivan, Neil P.
"Extent and Consistency of Linkage Disequilibrium and
Identification of DNA Markers for Production and Egg Quality
Traits in Commercial Layer Chicken Populations,"
Animal Industry Report:
AS 655, ASL R2444.
Available at: http://lib.dr.iastate.edu/ans_air/vol655/iss1/67