Summary and Implications
Large scale gene expression studies expedite the discovery process and provide a comprehensive view of host immune response. We used the Affymetrix GeneChip chicken genome array to determine the nature and breadth of the gene activation elicited by endotoxin from Salmonella typhimirium (ST) 798. The data obtained from this type of research are important to improve vaccine development efficacy and to enhance animal health and food safety. Our findings may contribute to elucidation of disease response pathways.
Iowa State University
Ciraci, Ceren; Tuggle, Christopher K.; Wannemuehler, Michael J.; Nettleton, Daniel S.; and Lamont, Susan J.
"Kinetic Profile of Chicken Macrophage Immune Response
upon exposure to Salmonella-derived Endotoxin,"
Animal Industry Report:
AS 656, ASL R2481.
Available at: http://lib.dr.iastate.edu/ans_air/vol656/iss1/2