Summary and Implications
Selection to enhance immune response is difficult. Gene expression was assessed in two advanced intercross lines of chickens for various immune-related genes. Single nucleotide polymorphisms, SNPs, were identified in regions local to each gene and around a distant transcription factor, NF-Kappa-B, NFKB. These SNPs were used to identify expression QTL, eQTL, to aid in selection of immune gene expression. These eQTL may provide effective resources to which marker assisted selection may be applied.
Iowa State University
Sandford, Erin; Ciraci, Ceren; Abasht, Behnam; Dekkers, Jack C.M.; and Lamont, Susan J.
"SNPs in Region of NF-Kappa-B Gene Associated with Expression
of Immune-Related Genes,"
Animal Industry Report:
AS 656, ASL R2483.
Available at: http://lib.dr.iastate.edu/ans_air/vol656/iss1/4