Pig uterine endometrium undergoes significant transcriptional and translational reorganization during the course of the estrous cycle and during early pregnancy establishment. The expression of two RNA binding proteins, DND1 and FXR1, was analyzed from samples of endometrial tissue taken on different days of either the estrous cycle or gestation. Expression of FXR1 is significantly affected by day of estrous cycle, while DND1 expression is not. Using immunohistochemistry DND1 protein expression was demonstrated to occur primarily in luminal epithelial cells of the uterine endometrium.