Summary and Implications
Exotic Newcastle Disease Virus (ENDV) cause extremely rapid mortality in chickens after exposure to the virus. People rely heavily on poultry to provide protein and income in many places where NDV is not effectively controlled through vaccination and biosecurity. Losses from NDV contribute to worldwide hunger and poverty. It may be possible to use genetic selection to produce chickens that have a stronger immune response in the face of NDV challenge. For genetic selection to be successful, two major elements are required: differences in immune response among chickens and genetic control of these differences. This study clearly demonstrated the existence of both these factors. These findings demonstrate the feasibility of genetic selection to produce chickens that are more resistant to NDV and thereby lessen the burdens of hunger and poverty.
Iowa State University
Rowland, Kaylee; Zhou, Huaijun; Gallardo, Rodrigo; Bunn, David; and Lamont, Susan J.
"Infection of Commercial Laying Hens with Newcastle Disease Virus: Differing Responses between Birds Provide Potential for Genetic Improvement through Selection,"
Animal Industry Report:
AS 662, ASL R3096.
Available at: http://lib.dr.iastate.edu/ans_air/vol662/iss1/57