Summary and Implications
Bone marrow antigen presenting cells (BM-APC), from Fayoumis (disease resistant and heat tolerant) and Leghorn (disease susceptible) chicken lines were evaluated for response to an inflammatory stimulus and heat stress. BM-APC from Fayoumis produced more nitric oxide (NO) and had higher Major Histocompatibility Complex (MHC) class II cell surface expression compared to those from Leghorn, indicating that BM-APC studied in vitro may be a useful tool to evaluate molecular effects of disease and/or heat tolerance in chickens.
Iowa State University
Van Goor, Angelica; Slawinska, Anna; Schmidt, Carl; and Lamont, Susan J.
"Unique Genetic Differences in Responses of Chicken Immune Cells to an Inflammatory Stimulus and Heat Stress,"
Animal Industry Report:
AS 662, ASL R3099.
Available at: http://lib.dr.iastate.edu/ans_air/vol662/iss1/60