Campus Units

Biochemistry, Biophysics and Molecular Biology, Zoology

Document Type

Article

Publication Version

Published Version

Publication Date

1983

Journal or Book Title

Cell Biology International Reports

Volume

7

Issue

7

First Page

527

Last Page

528

DOI

10.1016/0309-1651(83)90161-3

Abstract

We have shown that serum, fibroblast growth factor, epidermal growth factor, and the tumour promotor, 12-O-tetradecanoylphorbol- 13-acetate (TPA), selectively induce the synthesis of certain secreted proteins in a variety of cell types. Similarly, a specific growth inhibitor protein selectively induces the synthesis of a secreted protein that is different from those induced by growth factors. In each case, the average increase in labeling by [3%]methionine of these secreted proteins after their induction is 7- to 10-fold. No correspondingly large increase is detected for intracellular proteins.

Comments

This is an article from Cell Biology International Reports 7 (1983): 527, doi:10.1016/0309-1651(83)90161-3. Posted with permission.

Rights

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Copyright Owner

The Authors

Language

en

File Format

application/pdf

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