Campus Units

Biochemistry, Biophysics and Molecular Biology

Document Type

Article

Publication Version

Accepted Manuscript

Publication Date

2013

Journal or Book Title

Organic & Biomolecular Chemistry

Volume

11

Issue

44

First Page

7650

Last Page

7652

DOI

10.1039/C3OB41885E

Abstract

Miltiradiene (1), is the precursor of phenolic diterpenoids such as ferruginol (2), requiring aromatization and hydroxylation. While this has been attributed to a single cytochrome P450 (CYP76AH1), characterization of the rosemary ortholog CYP76AH4 led to the discovery that these CYPs simply hydroxylate the facilely oxidized aromatic intermediate abietatriene (3).

Comments

This is a manuscript of an article published as Zi, Jiachen, and Reuben J. Peters. "Characterization of CYP76AH4 clarifies phenolic diterpenoid biosynthesis in the Lamiaceae." Organic & biomolecular chemistry 11, no. 44 (2013): 7650-7652. doi: 10.1039/C3OB41885E. Posted with permission.

Copyright Owner

The Royal Society of Chemistry

Language

en

File Format

application/pdf

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