Transmissible mink encephalopathy (TME) is a progressive and fatal neurodegenerative disease that affects ranched mink (Neovison (Mustela) vison). Most or all of the adult animals on a ranch may be affected, and once an animal becomes symptomatic, death is inevitable. This disease is still poorly understood. It is very rare, with only a few outbreaks reported in the U.S. and other countries. Outbreaks seem to result from feeding contaminated food containing prions to mink; however, the origin of these prions is unknown. Recent evidence suggests they might be an atypical variant of the bovine spongiform encephalopathy (BSE) agent.
Iowa State University
Iowa State University Center for Food Security and Public Health, "Transmissible Mink Encephalopathy" (2016). Center for Food Security and Public Health Technical Factsheets. 136.