An aged mule entered the clinic on Jan. 27, 1947, presenting a history of having been cut on the plantar surface of the left hind leg at the middle of the metatarsal- region. The mule had been injured some 3 or 4 weeks previously and home remedies of an unknown origin had been employed as the only treatment. Extensive granulation tissue had formed at the site of injury and the owner asked to "do what you can for him." As a matter of second thought the owner mentioned that he thought the mule had been shot with a shotgun, because of the numerous "little bumps in the skin" of the shoulder region. Little thought was given at the time to the lesions of the shoulder but later they proved quite interesting. The exhuberant granulation tissue of the hind leg was treated in the usual manner with poor results as is so often the case, but since this report is more concerned with the lesions of the shoulder rather than the mule in general, we will confine ourselves to that area.