Pediocin (ALTA™ 2341) was studied in combination with irradiation treatments for control of Listeria monocytogenes on ready-to-eat (RTE) meat products. Both pediocin and irradiation were effective but the combination was highly effective and synergistic. Therefore, the use of pediocin for RTE meats that are irradiated should permit use of lower irradiation doses and improved product quality because of less irradiation-induced off-odors