This research examines the process (and impact) of foreign technical assistance to government primary health care systems in developing countries in terms of enhancing accessibility, program effectiveness, and sustainability. The research describes how the African and Cuban health care systems work to meet the needs of their underserved, primarily rural populations, how these populations' access to health care services are addressed, and how the Cuban assistance affects the ability of nations in the Global South to achieve their goals of providing quality health care for their populations. More specifically, the research examines the Cuban government's multi-faceted assistance to primary health care systems in sub-Saharan Africa. This research examines the experiences of the Cuban Medical Brigade in Ghana in terms of their approach to addressing issues of accessibility and capacity building as indicators of program appropriateness.