Enabling broad use of genome modification technologies to solve real world problems: a specific application in peanut
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The Department of Agronomy seeks to teach the study of the farm-field, its crops, and its science and management. It originally consisted of three sub-departments to do this: Soils, Farm-Crops, and Agricultural Engineering (which became its own department in 1907). Today, the department teaches crop sciences and breeding, soil sciences, meteorology, agroecology, and biotechnology.
History
The Department of Agronomy was formed in 1902. From 1917 to 1935 it was known as the Department of Farm Crops and Soils.
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1902–present
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- Department of Farm Crops and Soils (1917–1935)
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- College of Agriculture and Life Sciences (parent college)
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Abstract
Researchers estimate that up to fifteen million Americans have food allergies. Of those affected, peanut allergies account for the highest number of deaths per year of any other food borne allergen. Although several peanut proteins have been identified for their role in triggering human immune response, there are four main proteins responsible for the hypersensitive reaction: Ara h 1, Ara h 2, Ara h 3, and Ara h 6. Anaphylaxis (an acute allergic reaction) is triggered by peanut in sensitive individuals, by hypersensitive immune response to the Ara h 2 protein, which has been found to be the most severely allergenic of the 4 genes. Here we use the CRISPR Genome Analysis Tool (CGAT) along with other bioinformatics techniques to propose a methodology for the targeted deletion of the Ara h 1 peanut allergen