A flexible route to bioactive 6-alkyl-α-pyrones
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The Department of Chemistry seeks to provide students with a foundation in the fundamentals and application of chemical theories and processes of the lab. Thus prepared they me pursue careers as teachers, industry supervisors, or research chemists in a variety of domains (governmental, academic, etc).
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The Department of Chemistry was founded in 1880.
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1880-present
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- College of Liberal Arts and Sciences (parent college)
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Abstract
Both 6-chloro-α-pyrones and 3-chlorobenzopyran-1-ones react with malonates followed by a double decarboalkoxylation to give the corresponding alkyl and alkenyl products.
Comments
This is a manuscript of an article published as Qu, Yang, and George A. Kraus. "A flexible route to bioactive 6-alkyl-α-pyrones." Tetrahedron Letters 58, no. 9 (2017): 892-893. doi: 10.1016/j.tetlet.2017.01.063. Posted with permission.