A direct synthesis of atractylodinol, a potent inhibitor of PRRSV, and its biological evaluation
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The Department of Animal Science originally concerned itself with teaching the selection, breeding, feeding and care of livestock. Today it continues this study of the symbiotic relationship between animals and humans, with practical focuses on agribusiness, science, and animal management.
History
The Department of Animal Husbandry was established in 1898. The name of the department was changed to the Department of Animal Science in 1962. The Department of Poultry Science was merged into the department in 1971.
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- Department of Animal Husbandry (1898–1962)
- College of Agricultural and Life Sciences (parent college)
- Department of Poultry Science (merged with, 1971)
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The Department of Chemistry seeks to provide students with a foundation in the fundamentals and application of chemical theories and processes of the lab. Thus prepared they me pursue careers as teachers, industry supervisors, or research chemists in a variety of domains (governmental, academic, etc).
History
The Department of Chemistry was founded in 1880.
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1880-present
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- College of Liberal Arts and Sciences (parent college)
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Abstract
A direct synthesis of atractylodinol from 2-furylbutenyne and bromoacetylene 6 is reported. Both compounds 1 and 8 showed greater than 99% virus inhibition.
Comments
This is a manuscript of an article published as Kraus, George A., Pengfei Dong, Yang Qu, Alyssa Evans, and Susan Carpenter. "A direct synthesis of atractylodinol, a potent inhibitor of PRRSV, and its biological evaluation." Tetrahedron Letters 57, no. 47 (2016): 5185-5187. DOI: 10.1016/j.tetlet.2016.10.014. Posted with permission.