Document Type

Article

Publication Date

2010

Journal or Book Title

Toxins

Volume

2

Issue

5

First Page

935

Last Page

953

DOI

10.3390/toxins2050935

Abstract

Proteases from a variety of sources (viruses, bacteria, fungi, plants, and insects) have toxicity towards insects. Some of these insecticidal proteases evolved as venom components, herbivore resistance factors, or microbial pathogenicity factors, while other proteases play roles in insect development or digestion, but exert an insecticidal effect when over-expressed from genetically engineered plants or microbial pathogens. Many of these proteases are cysteine proteases, although insect-toxic metalloproteases and serine proteases have also been examined. The sites of protease toxic activity range from the insect midgut to the hemocoel (body cavity) to the cuticle. This review discusses these insecticidal proteases along with their evaluation and use as potential pesticides.

Comments

This article is from Toxins 2, no. 5 (2010): 935–953, doi:10.3390/toxins2050935.

Rights

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

Copyright Owner

The authors

Language

en

File Format

application/pdf

Included in

Entomology Commons

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