Campus Units

Agronomy, Entomology, Biosafety Institute for Genetically Modified Agricultural Products

Document Type

Article

Publication Version

Published Version

Publication Date

11-2008

Journal or Book Title

Journal of Agriculture and Food Chemistry

Volume

56

Issue

23

First Page

11342

Last Page

11347

DOI

10.1021/jf802355a

Abstract

The ecotoxicological effects of transgenic maize-expressed vaccine protein, Escherichia coliheat-labile enterotoxin subunit B (LTB), on two soil invertebrates were studied under laboratory settings. After being reared for 28 days on LTB-maize-treated soils, no apparent mortality of the springtail, Folsomia candida, or the earthworm, Eisenia fetida, was observed at levels well above conservatively projected estimated environmental concentrations. Therefore, it is concluded that there would be no acutely toxic effect of LTB to these species. As for the subacute effect, no significant differences of F. candida mean reproduction and E. fetida mean growth were observed between LTB-maize-treated samples and non-GM-maize-treated controls. In addition, no LTB was detected in the E. fetida whole-body extraction assay, which indicates there was no tendency for bioaccumulation. On the basis of these observations, it is predicted that any adverse effects of LTB-maize on F. candida and E. fetidawould be minimal, if any.

Comments

Reprinted with permission from Journal of Agriculture and Food Chemistry 56 (2008): 11342, doi:10.1021/jf802355a. Copyright 2008 American Chemical Society.

Copyright Owner

American Chemical Society

Language

en

File Format

application/pdf

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