Subacute Effects of Maize-Expressed Vaccine Protein, Escherichia coli Heat-Labile Enterotoxin Subunit B (LTB), on the Springtail, Folsomia candida, and the Earthworm, Eisenia fetida

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2008-11-01
Authors
Kosaki, Hirofumi
Wolt, Jeffrey
Wang, Kan
Coats, Joel
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Coats, Joel
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Agronomy

The Department of Agronomy seeks to teach the study of the farm-field, its crops, and its science and management. It originally consisted of three sub-departments to do this: Soils, Farm-Crops, and Agricultural Engineering (which became its own department in 1907). Today, the department teaches crop sciences and breeding, soil sciences, meteorology, agroecology, and biotechnology.

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The Department of Agronomy was formed in 1902. From 1917 to 1935 it was known as the Department of Farm Crops and Soils.

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1902–present

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  • Department of Farm Crops and Soils (1917–1935)

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Entomology

The Department of Entomology seeks to teach the study of insects, their life-cycles, and the practicalities in dealing with them, for use in the fields of business, industry, education, and public health. The study of entomology can be applied towards evolution and ecological sciences, and insects’ relationships with other organisms & humans, or towards an agricultural or horticultural focus, focusing more on pest-control and management.

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The Department of Entomology was founded in 1975 as a result of the division of the Department of Zoology and Entomology.

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AgronomyEntomologyBiosafety Institute for Genetically Modified Agricultural Products
Abstract

The ecotoxicological effects of transgenic maize-expressed vaccine protein, Escherichia coliheat-labile enterotoxin subunit B (LTB), on two soil invertebrates were studied under laboratory settings. After being reared for 28 days on LTB-maize-treated soils, no apparent mortality of the springtail, Folsomia candida, or the earthworm, Eisenia fetida, was observed at levels well above conservatively projected estimated environmental concentrations. Therefore, it is concluded that there would be no acutely toxic effect of LTB to these species. As for the subacute effect, no significant differences of F. candida mean reproduction and E. fetida mean growth were observed between LTB-maize-treated samples and non-GM-maize-treated controls. In addition, no LTB was detected in the E. fetida whole-body extraction assay, which indicates there was no tendency for bioaccumulation. On the basis of these observations, it is predicted that any adverse effects of LTB-maize on F. candida and E. fetidawould be minimal, if any.

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Reprinted with permission from Journal of Agriculture and Food Chemistry 56 (2008): 11342, doi:10.1021/jf802355a. Copyright 2008 American Chemical Society.

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Tue Jan 01 00:00:00 UTC 2008
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