Applications of single molecule and nanoparticle imaging in chemical separation, photocatalysis, and drug delivery
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The Department of Chemistry seeks to provide students with a foundation in the fundamentals and application of chemical theories and processes of the lab. Thus prepared they me pursue careers as teachers, industry supervisors, or research chemists in a variety of domains (governmental, academic, etc).
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The Department of Chemistry was founded in 1880.
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1880-present
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- College of Liberal Arts and Sciences (parent college)
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Abstract
This dissertation includes five chapters. Chapter 1 introduces single molecule and nanoparticle imaging techniques and their applications. Chapter 2 is a study of electrophoretic migration and axial diffusion of single nanoparticles in cylindrical nanopores in which the liquid viscosity was successfully measured. Chapter 3 reports the use of gold nanoparticles as drug delivery carriers and imaging contrast probes to study stem cell proliferation. This is an effort to maximize the capabilities of the recently developed plasmonic nanoparticle imaging techniques in stem cell research. Chapter 4 reports a study of single molecule catalysis on a modular multilayer catalytic platform and demonstrates three-dimensional super-localization imaging of single turnover events on 200-nm nanocatalysts. Chapter 5 summarizes all of the contents in the dissertation.