Document Type

Article

Publication Date

10-7-2008

Journal or Book Title

Applied Physics Letters

Volume

93

Issue

143107

First Page

1

Last Page

3

DOI

10.1063/1.2996411

Abstract

We report a sensor consisting of two micromachined cantilevers (a sensing/reference pair) that is suitable for detection of chemical and biological species. The sensing strategy involves coating the sensing cantilever with receptors that have high affinities for the analyte. The presence of analyte is detected by determining the differential surface stress associated with its adsorption/absorption to the sensing cantilever. An interferometric technique is utilized to measure the differential bending of the sensing cantilever with respect to reference. Surface stress associated with hybridization of single stranded DNA is measured to demonstrate the unique advantages of the sensor.

Comments

The following article appeared in Applied Physics Letters 93, 143107 (2008); and may be found at, doi:10.1063/1.2996411.

Rights

Copyright 2008 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics.

Copyright Owner

American Institute of Physics

Language

en

File Format

application/pdf

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