Document Type

Patent

Publication Date

9-19-1989

Abstract

A method of synthesizing nitrogen heterocycles such as indoles, indolines, oxindoles, quinolines, isoquinolines, and isoquinolones, all of which are pharmacologically active. The method involves cyclizing a haloaryl alkene in the presence of a catalytically effective amount of a palladium(II) ion source and in the presence of a cyclizing promoting base such as an alkali metal salt.

Patent Number

US 4,868,304

ISURF Reference Number

1084

Assignee

Iowa State University Research Foundation, Inc.,

Application Number

US 07/200,716

Date Filed

5-27-1988

Language

en

File Format

application/pdf

Included in

Chemistry Commons

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