Document Type

Patent

Publication Date

10-3-2006

Abstract

The present invention provides functional nucleic acid probes, and methods of using functional nucleic acid probes, for binding a target to carry out a desired function. The probes have at least one functional nucleic acid, at least one regulating nucleic acid, and at least one attenuator. The functional nucleic acid is maintained in an inactive state by the attenuator and activated by the regulating nucleic acid only in the presence of a regulating nucleic acid target. In its activated state the functional nucleic acid can bind to its target to carry out a desired function, such as generating a signal, cleaving a nucleic acid, or catalyzing a reaction.

Patent Number

US 7,115,369 B2

ISURF Reference Number

2711

Assignee

Iowa State University Research Foundation, Inc.,

Application Number

US 10/096,872

Date Filed

3-14-2002

Language

en

File Format

application/pdf

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