Document Type

Patent

Publication Date

11-13-2012

Abstract

Novel uses for diterpene modulators of macrophage phagosomal maturation are provided. The diterpene isotuberculosinol is used as an immune modulator, assay for pharmaceutical compositions and an isolated Mycobacterium tuberculosis labdane-related diterpenoid virulence factor. A method of treating Mycobacterium tuberculosis infectivity is further provided.

Patent Number

US 8,309,322 B2

Assignee

Iowa State University Research Foundation, Inc.; Cornell University

Application Number

12/776,759

Date Filed

5-10-2010

Language

en

File Format

application/pdf

Included in

Biochemistry Commons

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