A new mechanism for translational control in plants
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Abstract
In unstressed conditions, the cap‐binding protein, eIF4E, binds the 5′ cap structure (m7G) on mRNA and recruits other translation initiation factors to bring the ribosome to the mRNA. Bruns et al. show that, in plants, phosphorylation of eIF4E by the master metabolic regulatory protein, sucrose nonfermenting‐related kinase 1 (SnRK1), reduces translation globally. This negative regulation of translation inhibits geminivirus infection and is speculated to be a response to various abiotic stresses.
Comments
This is the peer reviewed version of the following article: Miller, W. Allen, and Savithramma P. Dinesh‐Kumar. "A new mechanism for translational control in plants." The FEBS Journal, which has been published in final form at doi: 10.1111/febs.15022. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.