The effect of hydrogen, deuterium and oxygen on the anelastic properties of V, Nb and V-Nb alloys were examined. Activation parameters were obtained for the oxygen Snoek peak in V and Nb with various hydrogen concentrations. Hydrogen was found not to affect these oxygen relaxation parameters. Thus no interaction of oxygen with hydrogen occurs in the pure metals. Measurement of the hydrogen Snoek peak and the deuterium Snoek peak in V-Nb alloys also fed to determination of activation parameters for these interstitials that· are consistent with those found by diffusion measurements in this same alloy series. An isotope effect was observed. In addition, oxygen was found not to affect the relaxation of the hydrogen in the V-Nb alloys, indicating that the oxygen-hydrogen interaction in the alloys is also negligible.