Alzheimer's disease is currently the fourth leading cause of death in adults (Alzheimer's Disease, 1994). Approximately four million Americans have Alzheimer's Disease, and an amazing 14 million are projected to have the disease by the middle of the next century unless a cure is found (Alzheimer's Disease, 1994; Iowa Department of Elder Affairs, 1992). Nearly 40 primary caregivers offered life stories of how Alzheimer's has impacted their lives. Spiritual, legal, financial, home modification, medical, and emotional needs were discussed by caregivers. Twelve in-depth interviews were conducted to gain greater insight into how practitioners in diverse fields can best help primary caregivers. A questionnaire was developed from the interviews to seek commonalties among caregivers on a greater scale. Primary caregivers stated needs, struggles, and satisfactions in caring for persons with Alzheimer's and suggested what would help them most in providing the best possible care. Results from this study provide (1) a brief history and definition of Alzheimer's Disease, (2) stages of caregiving in relation to the patient's status, (3) how Alzheimer's impacts primary caregivers needs, struggles, satisfactions, and meaning-making, and (4) how practitioners from diverse fields can best help primary caregivers.