Campus Units

Statistics, Veterinary Microbiology and Preventive Medicine, Veterinary Diagnostic and Production Animal Medicine

Document Type

Article

Publication Version

Published Version

Publication Date

4-2014

Journal or Book Title

BMC Veterinary Research

Volume

10

First Page

1

Last Page

8

DOI

10.1186/1746-6148-10-89

Abstract

Bibersteinia trehalosi causes respiratory disease in ruminants particularly in wild and domestic sheep. Recently, there has been an increased number of B. trehalosi isolates obtained from diagnostic samples from bovine respiratory disease cases. This study evaluated the role of B. trehalosi in bovine respiratory disease using an intra-tracheal inoculation model in calves. Thirty six cross bred 2–3 month old dairy calves were inoculated intra-tracheally with either leukotoxin negative B. trehalosi, leukotoxin positive B. trehalosi isolate, Mannheimia haemolytica, a combination of leukotoxin negative B. trehalosi and M. haemolytica or negative control. Calves were euthanized and necropsy performed on day 10 of study. B. trehalosi inoculated calves did not have increased lung involvement compared to control calves. Additionally, B. trehalosiwas only cultured once from the lungs of inoculated calves at necropsy. Based on these findings B. trehalosi may not be a primary pathogen of respiratory disease in cattle. Culture of B. trehalosifrom diagnostic submissions should not be immediately identified as a primary cause of respiratory disease.

Comments

This article is from BMC Veterinary Research 10 (2014): 89, doi:10.1186/1746-6148-10-89. Posted with permission.

Rights

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Copyright Owner

Christy J. Hanthorn, et al

Language

en

File Format

application/pdf