Campus Units

Veterinary Diagnostic and Production Animal Medicine, Agricultural and Biosystems Engineering, Statistics

Document Type

Article

Publication Version

Published Version

Publication Date

4-2013

Journal or Book Title

The Canadian Journal of Veterinary Research

Volume

77

Issue

2

First Page

95

Last Page

99

Abstract

In aerobiology, dose-response studies are used to estimate the risk of infection to a susceptible host presented by exposure to a specific dose of an airborne pathogen. In the research setting, host- and pathogen-specific factors that affect the dose-response continuum can be accounted for by experimental design, but the requirement to precisely determine the dose of infectious pathogen to which the host was exposed is often challenging. By definition, quantification of viable airborne pathogens is based on the culture of micro-organisms, but some airborne pathogens are transmissible at concentrations below the threshold of quantification by culture. In this paper we present an approach to the calculation of exposure dose at microbiologically unquantifiable levels using an application of the “continuous-stirred tank reactor (CSTR) model” and the validation of this approach using rhodamine B dye as a surrogate for aerosolized microbial pathogens in a dynamic aerosol toroid (DAT).

Comments

This article is from The Canadian Journal of Veterinary Research 77 (2013): 95. Posted with permission.

Copyright Owner

Canadian Veterinary Medical Association

Language

en

File Format

application/pdf