Campus Units

Veterinary Diagnostic and Production Animal Medicine, Statistics, Veterinary Clinical Sciences

Document Type

Article

Publication Version

Published Version

Publication Date

2010

Journal or Book Title

American Journal of Veterinary Research

Volume

71

Issue

9

First Page

1081

Last Page

1088

DOI

10.2460/ajvr.71.9.1081

Abstract

Objective—To evaluate the effects of various flow rates of oxygen administered via 1 or 2 nasal cannulae on the fraction of inspired oxygen concentration (Fio2) and other arterial blood gas variables in healthy neonatal foals.

Animals—9 healthy neonatal (3- to 4-day-old) foals.

Procedures—In each foal, a nasal cannula was introduced into each naris and passed into the nasopharynx to the level of the medial canthus of each eye; oxygen was administered at 4 flow rates through either 1 or both cannulae (8 treatments/foal). Intratracheal Fio2, intratracheal end-tidal partial pressure of carbon dioxide, and arterial blood gas variables were measured before (baseline) and during unilateral and bilateral nasopharyngeal delivery of 50, 100, 150, and 200 mL of oxygen/kg/min.

Results—No adverse reactions were associated with administration of supplemental oxygen except at the highest flow rate, at which the foals became agitated. At individual flow rates, significant and dose-dependent increases in Fio2, Pao2, and oxygen saturation of hemoglobin (Sao2) were detected, compared with baseline values. Comparison of unilateral and bilateral delivery of oxygen at similar cumulative flow rates revealed no differences in evaluated variables.

Conclusions and Clinical Relevance—Results indicated that administration of supplemental oxygen via nasal cannulae appeared to be a highly effective means of increasing Fio2, Pao2, and Sao2 in neonatal foals. These findings may provide guidance for implementation of oxygen treatment in hypoxemic neonatal foals.

Comments

This article is from American Journal of Veterinary Research 71 (2010): 1081, doi: 10.2460/ajvr.71.9.1081. Posted with permission.

Copyright Owner

American Veterinary Medical Association

Language

en

File Format

application/pdf