Agricultural and Biosystems Engineering Publications

Campus Units

Agricultural and Biosystems Engineering, Chemistry, Civil, Construction and Environmental Engineering, Food Science and Human Nutrition, Veterinary Diagnostic and Production Animal Medicine, Environmental Science, Toxicology

Document Type

Article

Publication Version

Published Version

Publication Date

3-18-2021

Journal or Book Title

Agriculture

Volume

11

Issue

3

First Page

259

Research Focus Area(s)

Animal Production Systems Engineering

DOI

10.3390/agriculture11030259

Abstract

Proper treatment of infectious air could potentially mitigate the spread of airborne viruses such as porcine reproductive and respiratory syndrome virus (PRRSV). The objective of this research is to test the effectiveness of ultraviolet (UV) in inactivating aerosolized PRRSV, specifically, four UV lamps, UV-A (365 nm, both fluorescent and LED-based), “excimer” UV-C (222 nm), and germicidal UV-C (254 nm), were tested. The two UV-C lamps effectively irradiated fast-moving PRRSV aerosols with short treatment times (<2 s). One-stage and two-stage UV inactivation models estimated the UV doses needed for target percentage (%) reductions on PRRSV titer. UV-C (254 nm) dose needed for 3-log (99.9%) reduction was 0.521 and 0.0943 mJ/cm2, respectively, based on one-stage and two-stage models. An order of magnitude lower UV-C (222 nm) doses were needed for a 3-log reduction, i.e., 0.0882 and 0.048 mJ/cm2, based on one-stage and two-stage models, respectively. However, the cost of 222 nm excimer lamps is still economically prohibitive for scaling-up trials. The UV-A (365 nm) lamps could not reduce PRRSV titers for tested doses up to 4.11 mJ/cm2. Pilot-scale or farm-scale testing of UV-C on PRRSV aerosols simulating barn ventilation rates are recommended based on its effectiveness and reasonable costs comparable to HEPA filtration

Comments

This article is published as Li, Peiyang, Jacek A. Koziel, Jeffrey J. Zimmerman, Jianqiang Zhang, Ting-Yu Cheng, Wannarat Yim-Im, William S. Jenks, Myeongseong Lee, Baitong Chen, and Steven J. Hoff. "Mitigation of Airborne PRRSV Transmission with UV Light Treatment: Proof-of-Concept." Agriculture 11, no. 3 (2021): 259. DOI: 10.3390/agriculture11030259. Posted with permission.

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Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

Copyright Owner

The Author(s)

Language

en

File Format

application/pdf

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