Ames Laboratory; Chemistry
Ames Laboratory, Chemistry
A palladium(II)‐functionalized covalent organic framework (Pd@TpBpy COF) constructed from 1,3,5‐triformylphloroglucinol (Tp) and [2,2′‐bipyridine]‐5,5′‐diamine (Bpy) is reported as a recyclable catalyst for conjugate additions in aqueous media. Additions of an array of stereoelectronically diverse arylboronic acid nucleophiles to β,β‐disubstituted enones form a variety of ketones containing benzylic all‐carbon quaternary centers in up to 92 % isolated yield. Studies on the recyclability of Pd@TpBpy COF show this catalyst remains active through at least 7 cycles and shows superior stability to related MOF catalysts with bipyridine linker units.
DOE Contract Number(s)
Department of Energy Subject Categories
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Iowa State University Digital Repository, Ames IA (United States)