Summary and Implications
Gene expression changes after exposure to acute heatstress and/or to bacteriallipopolysaccharide (LPS) were investigated by measuring globalgene expression in two immune organs,bursa and thymus,from two chicken lines, Fayoumi and broiler. Over 1,600genes had significant expression changes in response to treatment; greaternumberswere identified in bursa for Fayoumi and in thymus forbroilers. Heat stress suppressed gene expression responses to LPS in both tissues.Both Heat and LPS impacted expression of immune cell traffickinggenes; these pathwaysneed to be investigated for potential to improve immune responses in heat-stressed chickens.
Iowa State University
Monson, Melissa S.; Van Goor, Angelica G.; Ashwell, Christopher M.; Persia, Michael E.; Rothschild, Max F.; Schmidt, Carl J.; and Lamont, Susan J.
"Exposure to Heat Stress and anImmune Stimulus AffectsGene Expression in Chicken Immune Tissues,"
Animal Industry Report:
AS 663, ASL R3174.
Available at: https://lib.dr.iastate.edu/ans_air/vol663/iss1/47