Summary and Implications
The objective of this study was to identify new ways to determine the severity of fescue toxicosis and identify genetic differences in fescue impacted traits as a basis in understanding how cattle could be selected for tolerance to fescue toxicosis. We identified across breed and within breed differences in heat stress related traits and growth rate in pregnant cows exposed to toxic fescue. In addition, new biomarkers were identified to differentiate susceptible and tolerant cattle in the form of specific fecal and vaginal microbes. Finally, we identified differentially expressed (DE) genes in high versus low tolerant cattle on toxic fescue. These findings may allow more accurate diagnosis of fescue toxicosis and provide a glimpse into the genes and microorganisms that may impact tolerance or susceptibility to toxic fescue.
Iowa State University
Koltes, James E.; Poole, Daniel H.; Schmitz-Esser, Stephan; Zhao, Jiangchao; Chewning, Sarah; Hubbell, Don III; and Serão, Nick V. L.
"Development of New Measurements and Tools to Mitigate Fescue Toxicosis in Beef Cattle,"
Animal Industry Report:
AS 664, ASL R3229.
Available at: https://lib.dr.iastate.edu/ans_air/vol664/iss1/27