Authors

Gane Ka-Shu Wong, Beijing Institute of Genomics of Chinese Academy of Sciences
Bin Liu, Beijing Institute of Genomics of Chinese Academy of Sciences
Jun Wang, Beijing Institute of Genomics of Chinese Academy of Sciences
Yong Zhang, Beijing Institute of Genomics of Chinese Academy of Sciences
Xu Yang, Beijing Institute of Genomics of Chinese Academy of Sciences
Zengjin Zhang, Beijing Institute of Genomics of Chinese Academy of Sciences
Qingshun Meng, Beijing Institute of Genomics of Chinese Academy of Sciences
Jun Zhou, Beijing Institute of Genomics of Chinese Academy of Sciences
Dawei Li, Beijing Institute of Genomics of Chinese Academy of Sciences
Jingjing Zhang, Beijing Institute of Genomics of Chinese Academy of Sciences
Peixiang Ni, Beijing Institute of Genomics of Chinese Academy of Sciences
Songgang Li, Beijing Institute of Genomics of Chinese Academy of Sciences
Longhua Ran, Beijing North Computation Center
Heng Li, Beijing Institute of Genomics of Chinese Academy of Sciences
Jianguo Zhang, Beijing Institute of Genomics of Chinese Academy of Sciences
Ruiqiang Li, Beijing Institute of Genomics of Chinese Academy of Sciences
Shengting Li, Beijing Institute of Genomics of Chinese Academy of Sciences
Hongkun Zheng, Beijing Institute of Genomics of Chinese Academy of Sciences
Wei Lin, Beijing Institute of Genomics of Chinese Academy of Sciences
Guangyuan Li, Beijing Institute of Genomics of Chinese Academy of Sciences
Xiaoling Wang, Beijing Institute of Genomics of Chinese Academy of Sciences
Wenming Zhao, Beijing Institute of Genomics of Chinese Academy of Sciences
Jun Li, Beijing Institute of Genomics of Chinese Academy of Sciences
Chen Ye, Beijing Institute of Genomics of Chinese Academy of Sciences
Mingtao Dai, Beijing Institute of Genomics of Chinese Academy of Sciences
Jue Ruan, Beijing Institute of Genomics of Chinese Academy of Sciences
Yan Zhou, James D. Watson Institute of Genome Sciences of Zhejiang University
Yuanzhe Li, Beijing Institute of Genomics of Chinese Academy of Sciences
Ximiao He, Beijing Institute of Genomics of Chinese Academy of Sciences
Yunze Zhang, Beijing Institute of Genomics of Chinese Academy of Sciences
Jing Wang, Beijing Institute of Genomics of Chinese Academy of Sciences
Xiangang Huang, Beijing Institute of Genomics of Chinese Academy of Sciences
Wei Tong, Beijing Institute of Genomics of Chinese Academy of Sciences
Jie Chen, Beijing Institute of Genomics of Chinese Academy of Sciences
Jia Ye, Beijing Institute of Genomics of Chinese Academy of Sciences
Chen Chen, Beijing Institute of Genomics of Chinese Academy of Sciences
Ning Wei, Beijing Institute of Genomics of Chinese Academy of Sciences
Guoqing Li, Beijing Institute of Genomics of Chinese Academy of Sciences
Le Dong, Beijing Institute of Genomics of Chinese Academy of Sciences
Fengdi Land, Beijing Institute of Genomics of Chinese Academy of Sciences
Yongqiao Sun, Beijing Institute of Genomics of Chinese Academy of Sciences
Zhenpeng Zhang, Beijing Institute of Genomics of Chinese Academy of Sciences
Zheng Yang, Beijing Institute of Genomics of Chinese Academy of Sciences
Yingpu Yu, James D. Watson Institute of Genome Sciences of Zhejiang University
Yanqing Huang, Beijing Institute of Genomics of Chinese Academy of Sciences
Dandan He, Beijing Institute of Genomics of Chinese Academy of Sciences
Yan Xi, Beijing Institute of Genomics of Chinese Academy of Sciences
Dong Wei, Beijing Institute of Genomics of Chinese Academy of Sciences
Qiuhui Qi, Beijing Institute of Genomics of Chinese Academy of Sciences
Wenjie Li, Beijing Institute of Genomics of Chinese Academy of Sciences
Jianping Shi, Beijing Institute of Genomics of Chinese Academy of Sciences
Miaoheng Wang, Beijing Institute of Genomics of Chinese Academy of Sciences
Fei Xie, Beijing Institute of Genomics of Chinese Academy of Sciences
Jianjun Wang, Beijing Institute of Genomics of Chinese Academy of Sciences
Xiaowei Zhang, Beijing Institute of Genomics of Chinese Academy of Sciences
Pei Wang, Beijing Institute of Genomics of Chinese Academy of Sciences
Yiqiang Zhao, China Agricultural University
Ning Li, China Agricultural University
Ning Yang, China Agricultural University
Wei Dong, Beijing Institute of Genomics of Chinese Academy of Sciences
Songnian Hu, Beijing Institute of Genomics of Chinese Academy of Sciences
Changqing Zeng, Beijing Institute of Genomics of Chinese Academy of Sciences
Weimou Zheng, Beijing Institute of Genomics of Chinese Academy of Sciences
Bailin Hao, Beijing Institute of Genomics of Chinese Academy of Sciences
LaDeana W. Hillier, Washington University School of Medicine
Shiaw-Pyng Yang, Washington University School of Medicine
Wesley C. Warren, Washington University School of Medicine
Richard K. Wilson, Washington University School of Medicine
Mikael Brandstrom, Uppsala University
Hans Ellegren, Uppsala University
Richard P. M. A. Crooijmans, Wageningen University
Jan J. van der Poel, Wageningen University
Henk Bovenhuis, Wageningen University
Martien A. M. Groenen, Wageningen University
Ivan Ovcharenko, Lawrence Livermore National Laboratory
Laurie Gordon, Lawrence Livermore National Laboratory
Lisa Stubbs, Lawrence Livermore National Laboratory
Susan Lucas, United States Department of Energy Joint Genome Institute
Tijana Glavina, United States Department of Energy Joint Genome Institute
Andrea Aerts, United States Department of Energy Joint Genome Institute
Pete Kaiser, Institute for Animal Health
Lisa Rothwell, Institute for Animal Health
John R. Young, Institute for Animal Health
Sally Rogers, Institute for Animal Health
Brian A. Walker, Institute for Animal Health
Andy van Hateren, Institute for Animal Health
Jim Kaufman, Institute for Animal Health
Nat Bumstead, Institute for Animal Health
Susan J. Lamont, Iowa State UniversityFollow
Huaijun Zhou, Iowa State University
Paul M. Hocking, Roslin Institute
David Morrice, Roslin Institute
Dirk-Jan de Koning, Roslin Institute
Andy Law, Roslin Institute
Neil Bartly, Roslin Institute
David W. Burt, Roslin Institute
Henry Hunt, United States Department of Agriculture
Hans H. Cheng, United States Department of Agriculture
Ulrika Gunnarsson, Uppsala University
Per Wahlberg, Uppsala University
Leif Andersson, Uppsala University
Ellen Kindlund, Karolinska Institutet
Martti T. Tammi, Karolinska Institutet
Björn Andersson, Karolinska Institutet
Caleb Webber, University of Oxford
Chris P. Ponting, University of Oxford
Ian M. Overton, University of Manchester Institute of Science and Technology
Paul E. Boardman, University of Manchester Institute of Science and Technology
Haizhou Tang, University of Manchester Institute of Science and Technology
Simon J. Hubbard, University of Manchester Institute of Science and Technology
Stuart A. Wilson, University of Sheffield
Jun Yu, Beijing Institute of Genomics of Chinese Academy of Sciences
Jian Wang, Beijing Institute of Genomics of Chinese Academy of Sciences
HuanMing Yang, Beijing Institute of Genomics of Chinese Academy of Sciences
International Chicken Polymorphism Map Consortium

Document Type

Article

Publication Version

Published Version

Publication Date

12-2004

Journal or Book Title

Nature

Volume

432

First Page

717

Last Page

722

DOI

10.1038/nature03156

Abstract

We describe a genetic variation map for the chicken genome containing 2.8 million single-nucleotide polymorphisms (SNPs). This map is based on a comparison of the sequences of three domestic chicken breeds (a broiler, a layer and a Chinese silkie) with that of their wild ancestor, red jungle fowl. Subsequent experiments indicate that at least 90% of the variant sites are true SNPs, and at least 70% are common SNPs that segregate in many domestic breeds. Mean nucleotide diversity is about five SNPs per kilobase for almost every possible comparison between red jungle fowl and domestic lines, between two different domestic lines, and within domestic lines—in contrast to the notion that domestic animals are highly inbred relative to their wild ancestors. In fact, most of the SNPs originated before domestication, and there is little evidence of selective sweeps for adaptive alleles on length scales greater than 100 kilobases.

Comments

This article is from Nature 432 (2004): 717, doi:10.1038/nature03156.

Rights

Works produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted.

Language

en

File Format

application/pdf

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