Campus Units
Animal Science
Document Type
Article
Publication Version
Published Version
Publication Date
2010
Journal or Book Title
BMC Genomics
Volume
11
Issue
438
First Page
1
Last Page
5
DOI
10.1186/1471-2164-11-438
Abstract
Background: The pig genome is being sequenced and characterised under the auspices of the Swine Genome Sequencing Consortium. The sequencing strategy followed a hybrid approach combining hierarchical shotgun sequencing of BAC clones and whole genome shotgun sequencing. Results: Assemblies of the BAC clone derived genome sequence have been annotated using the Pre-Ensembl and Ensembl automated pipelines and made accessible through the Pre-Ensembl/Ensembl browsers. The current annotated genome assembly (Sscrofa9) was released with Ensembl 56 in September 2009. A revised assembly (Sscrofa10) is under construction and will incorporate whole genome shotgun sequence (WGS) data providing > 30× genome coverage. The WGS sequence, most of which comprise short Illumina/Solexa reads, were generated from DNA from the same single Duroc sow as the source of the BAC library from which clones were preferentially selected for sequencing. In accordance with the Bermuda and Fort Lauderdale agreements and the more recent Toronto Statement the data have been released into public sequence repositories (Genbank/EMBL, NCBI/Ensembl trace repositories) in a timely manner and in advance of publication. Conclusions: In this marker paper, the Swine Genome Sequencing Consortium (SGSC) sets outs its plans for analysis of the pig genome sequence, for the application and publication of the results.
Rights
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright Owner
Archibald et al
Copyright Date
2010
Language
en
File Format
application/pdf
Recommended Citation
Archibald, Alan L.; Bolund, Lars; Churcher, Carol; Fredholm, Merete; Groenen, Martien A. M.; Harlizius, Barbara; Lee, Kyung-Tai; Milan, Denis; Rogers, Jane; Rothschild, Max F.; Uenishi, Hirohide; Wang, Jun; and Schook, Lawrence B., "Pig genome sequence - analysis and publication strategy" (2010). Animal Science Publications. 222.
https://lib.dr.iastate.edu/ans_pubs/222
Comments
This is an article from BMC Genomics 11 (2010): 1, doi:10.1186/1471-2164-11-438. Posted with permission.