Document Type
Article
Publication Date
12-2012
Journal or Book Title
Journal of Animal Science
Volume
90
Issue
Supplement 4
First Page
233
Last Page
235
DOI
10.2527/jas.53976
Abstract
Little is known of the consequences of divergent selection for residual feed intake (RFI) on intestinal digestion capacity, particularly during immune system stimulation (ISS). Our objective was to evaluate the impact of ISS and divergent selection for RFI on apparent ileal digestibility (AID) and apparent fecal digestibility (AFD) of nutrients and intestinal nutrient active transport and barrier function. Twenty-eight gilts (63 ± 4 kg BW) from low RFI (LRFI; n = 14) and high RFI (HRFI; n = 14) Yorkshire lines were randomly selected from the Iowa State University RFI herd. Following adaptation, 8 pigs in each line were injected intramuscularly and every 48 h for 7 d with increasing amounts of Escherichia colilipopolysaccharide (ISS+). Remaining pigs were injected with saline (ISS–). Pigs were then euthanized and ileal digesta was collected for measuring AID of nutrients. Fecal samples were collected on a daily basis and pooled for measuring AFD of nutrients. A segment of ileum was used to measure nutrient transport and transepithelial resistance (TER) and/or barrier integrity by Ussing chambers. No effects of line or its interaction with ISS on AID of CP (N × 6.25) and OM, TER, and active nutrients transport were observed. However, ISS decreased (P < 0.05) and tended to (P < 0.1) decrease AID of CP and OM, respectively. Decrease in AFD of CP as result of ISS was greater in the LRFI line compared to the HRFI line (P < 0.05). Relative to ISS–, active glucose and P transport was greater in ISS+ pigs (P < 0.05). Genetic selection for LRFI increases the AFD but has no effect on AID of nutrients. It also reduces the total tract digestive capacity of growing pigs during ISS. Immune system stimulation affects both AID and AFD of dietary CP.
Rights
Works produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted.
Language
en
File Format
application/pdf
Recommended Citation
Rakhshandeh, A.; Dekkers, Jack C. M.; Kerr, Brian J.; Weber, Thomas E.; English, J.; and Gabler, Nicholas K., "Effect of immune system stimulation and divergent selection for residual feed intake on digestive capacity of the small intestine in growing pigs" (2012). Animal Science Publications. 33.
https://lib.dr.iastate.edu/ans_pubs/33
Comments
This article is from Journal of Animal Science 90 (2012): 233–235, doi:10.2527/jas.53976.