Campus Units
Animal Science
Document Type
Article
Publication Version
Published Version
Publication Date
1-8-2019
Journal or Book Title
Nucleic Acids Research
Volume
47
Issue
D1
First Page
D701
Last Page
D710
DOI
10.1093/nar/gky1084
Abstract
Successful development of biological databases requires accommodation of the burgeoning amounts of data from high-throughput genomics pipelines. As the volume of curated data in Animal QTLdb (https://www.animalgenome.org/QTLdb) increases exponentially, the resulting challenges must be met with rapid infrastructure development to effectively accommodate abundant data curation and make metadata analysis more powerful. The development of Animal QTLdb and CorrDB for the past 15 years has provided valuable tools for researchers to utilize a wealth of phenotype/genotype data to study the genetic architecture of livestock traits. We have focused our efforts on data curation, improved data quality maintenance, new tool developments, and database co-developments, in order to provide convenient platforms for users to query and analyze data. The database currently has 158 499 QTL/associations, 10 482 correlations and 1977 heritability data as a result of an average 32% data increase per year. In addition, we have made >14 functional improvements or new tool implementations since our last report. Our ultimate goals of database development are to provide infrastructure for data collection, curation, and annotation, and more importantly, to support innovated data structure for new types of data mining, data reanalysis, and networked genetic analysis that lead to the generation of new knowledge.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright Owner
The Authors
Copyright Date
2018
Language
en
File Format
application/pdf
Recommended Citation
Hu, Zhi-Liang; Park, Carissa A.; and Reecy, James M., "Building a livestock genetic and genomic information knowledgebase through integrative developments of Animal QTLdb and CorrDB" (2019). Animal Science Publications. 444.
https://lib.dr.iastate.edu/ans_pubs/444
Comments
This article is published as Hu, Zhi-Liang, Carissa A. Park, and James M. Reecy. "Building a livestock genetic and genomic information knowledgebase through integrative developments of Animal QTLdb and CorrDB." Nucleic acids research 47, no. D1 (2018): D701-D710. doi: 10.1093/nar/gky1084.