Campus Units

Animal Science

Document Type

Article

Publication Version

Published Version

Publication Date

12-1-2006

Journal or Book Title

Poultry Science

Volume

85

Issue

12

First Page

2061

Last Page

2078

DOI

10.1093/ps/85.12.2061

Abstract

A primary goal in the assessment of structural variation in the avian genome is to understand the relationship of this variation with biodiversity and with biological performance. To develop such knowledge, certain essential tools are needed. One set of tools includes the laboratory techniques used to assess molecular genetic variation. The current time is a transitional one for this field, in that the recently sequenced chicken genome will add significantly to the portfolio of existing methods used to identify molecular markers. To most efficiently discover marker-trait associations, the experimental mapping populations must be appropriately designed and the relevant statistical analyses applied. This paper reviews methods for assessment of molecular markers in poultry and their use in the characterization of avian biodiversity and in studies to identify marker associations with biological traits, including important considerations of population structure and statistical analysis.

Comments

This article is published as Soller, M., S. Weigend, Michael N. Romanov, J. C. M. Dekkers, and S. J. Lamont. "Strategies to assess structural variation in the chicken genome and its associations with biodiversity and biological performance." Poultry Science 85, no. 12 (2006): 2061-2078. DOI: 10.1093/ps/85.12.2061. Posted with permission.

Copyright Owner

Poultry Science Association Inc.

Language

en

File Format

application/pdf

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