Campus Units

Animal Science

Document Type

Article

Publication Version

Published Version

Publication Date

5-1-1987

Journal or Book Title

Poultry Science

Volume

66

Issue

5

First Page

790

Last Page

794

DOI

10.3382/ps.0660790

Abstract

The chicken major histocompatibility complex (MHC) exerts genetic influence over a variety of important biological functions including immune response, disease resistance, growth and development, aging, and reproduction. The chicken MHC possesses at least three subregions encoding distinct gene products. The B-G subregion encodes antigens unique to erythrocyte surfaces. The B-L and B-F subregions encode cell surface glycoproteins homologous to mammalian Class II and Class I antigens, respectively. Class I and Class II molecules are crucial for recognition of self vs. nonself and for cell communication, and therefore are fundamental for all immune responses. Studies of chromosomal recombinants have been particularly useful in eliciting the structure and function of subregions of the chicken MHC.

Comments

This article is published as Nordskog, A. W., I. Y. Pevzner, and S. J. Lamont. "Subregions and functions of the chicken major histocompatibility complex." Poultry Science 66, no. 5 (1987): 790-794. DOI: 10.3382/ps.0660790. Posted with permission.

Copyright Owner

Poultry Science Association Inc.

Language

en

File Format

application/pdf

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