Subregions and Functions of the Chicken Major Histocompatibility Complex
Date
Authors
Major Professor
Advisor
Committee Member
Journal Title
Journal ISSN
Volume Title
Publisher
Authors
Research Projects
Organizational Units
The Department of Animal Science originally concerned itself with teaching the selection, breeding, feeding and care of livestock. Today it continues this study of the symbiotic relationship between animals and humans, with practical focuses on agribusiness, science, and animal management.
History
The Department of Animal Husbandry was established in 1898. The name of the department was changed to the Department of Animal Science in 1962. The Department of Poultry Science was merged into the department in 1971.
Historical Names
- Department of Animal Husbandry (1898–1962)
- College of Agricultural and Life Sciences (parent college)
- Department of Poultry Science (merged with, 1971)
Related Units
Journal Issue
Is Version Of
Versions
Series
Department
Abstract
The chicken major histocompatibility complex (MHC) exerts genetic influence over a variety of important biological functions including immune response, disease resistance, growth and development, aging, and reproduction. The chicken MHC possesses at least three subregions encoding distinct gene products. The B-G subregion encodes antigens unique to erythrocyte surfaces. The B-L and B-F subregions encode cell surface glycoproteins homologous to mammalian Class II and Class I antigens, respectively. Class I and Class II molecules are crucial for recognition of self vs. nonself and for cell communication, and therefore are fundamental for all immune responses. Studies of chromosomal recombinants have been particularly useful in eliciting the structure and function of subregions of the chicken MHC.
Comments
This article is published as Nordskog, A. W., I. Y. Pevzner, and S. J. Lamont. "Subregions and functions of the chicken major histocompatibility complex." Poultry Science 66, no. 5 (1987): 790-794. DOI: 10.3382/ps.0660790. Posted with permission.