Campus Units
Biochemistry, Biophysics and Molecular Biology
Document Type
Article
Publication Version
Accepted Manuscript
Publication Date
2012
Journal or Book Title
MedChemComm
Volume
3
Issue
8
First Page
899
Last Page
904
DOI
10.1039/C2MD20030A
Abstract
The actinomycetes family of bacteria is classically considered a rich source of natural products [1]. It is often suggested that such compounds have been selected by evolution to have biological activity [2]. For example, given the microbial-rich soil environment of the actinomycetes native habitat, their natural products have been suggested to serve in chemical warfare and/or signaling, which has been further connected to their leading role in providing pharmaceutically relevant antibiotic agents [3]. Nevertheless, surprisingly few of these molecules have been definitively assigned specific physiological roles in the native producing bacteria.
Copyright Owner
The Royal Society of Chemistry
Copyright Date
2012
Language
en
File Format
application/pdf
Recommended Citation
Mann, Francis M. and Peters, Reuben J., "Isotuberculosinol: the unusual case of an immunomodulatory diterpenoid from Mycobacterium tuberculosis" (2012). Biochemistry, Biophysics and Molecular Biology Publications. 116.
https://lib.dr.iastate.edu/bbmb_ag_pubs/116
Included in
Bacteriology Commons, Biochemistry Commons, Molecular Biology Commons, Structural Biology Commons
Comments
This is a manuscript of an article published as Mann, F.M., Peters, R.J. (2012) “Isotuberculosinol: the unusual case of an immunomodulatory diterpenoid from Mycobacterium tuberculosis”, Med. Chem. Commun., 3(8):899-904, doi: 10.1039/C2MD20030A. Posted with permission.