Biochemistry, Biophysics and Molecular Biology, Roy J. Carver Department of
Journal or Book Title
Journal of Experimental Botany
Pyramiding R genes is a common strategy used by breeders to enhance resistance and increase durability of resistance in crops. However, the molecular mechanisms that mediate R gene interactions are not known. Kamphuis et al. (2019) analyzed Medicago truncatula plants carrying two genes that confer resistance to bluegreen aphids. They identified a potential phytohormone crosstalk triggered by the combined R gene action in response to aphid feeding that enhances resistance and minimizes R gene-associated fitness costs to the plant.
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Macintosh, Gustavo C., "Gene pyramids and the balancing act of keeping pests at bay" (2019). Biochemistry, Biophysics and Molecular Biology Publications. 258.