Campus Units
Biochemistry, Biophysics and Molecular Biology, Chemistry
Document Type
Article
Publication Version
Published Version
Publication Date
2008
Journal or Book Title
Molecules
Volume
13
Issue
4
First Page
986
Last Page
994
DOI
10.3390/molecules13040986
Abstract
A series of fluorinated analogs of malachite green (MG) have been synthesizedand their toxicity to Saccharomyces cerevisiae and a human ovarian epithelial cell lineexamined. The toxicity profiles were found to be different for these two species. Twoanalogs, one with 2,4-difluoro substitution and the other with 2-fluoro substitution seem tobe the most promising analogs because they showed the lowest toxicity to the human cells.
Rights
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright Owner
MDPI
Copyright Date
2008
Language
en
File Format
application/pdf
Recommended Citation
Kraus, George A.; Jeon, Insik; Nilsen-Hamilton, Marit; Awad, Ahmed M.; Banerjee, Jayeeta; and Parvin, Bahram, "Fluorinated Analogs of Malachite Green: Synthesis and Toxicity" (2008). Biochemistry, Biophysics and Molecular Biology Publications. 39.
https://lib.dr.iastate.edu/bbmb_ag_pubs/39
Comments
This is an article from Molecules 13 (2008): 986, doi:10.3390/molecules13040986. Posted with permission.