Biochemistry, Biophysics and Molecular Biology, Chemistry
Journal or Book Title
A series of fluorinated analogs of malachite green (MG) have been synthesizedand their toxicity to Saccharomyces cerevisiae and a human ovarian epithelial cell lineexamined. The toxicity profiles were found to be different for these two species. Twoanalogs, one with 2,4-difluoro substitution and the other with 2-fluoro substitution seem tobe the most promising analogs because they showed the lowest toxicity to the human cells.
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Kraus, George A.; Jeon, Insik; Nilsen-Hamilton, Marit; Awad, Ahmed M.; Banerjee, Jayeeta; and Parvin, Bahram, "Fluorinated Analogs of Malachite Green: Synthesis and Toxicity" (2008). Biochemistry, Biophysics and Molecular Biology Publications. 39.