Campus Units
Biochemistry, Biophysics and Molecular Biology, Mechanical Engineering
Document Type
Article
Publication Version
Published Version
Publication Date
2008
Journal or Book Title
Applied Physics Letters
Volume
93
First Page
143107
DOI
10.1063/1.2996411
Abstract
We report a sensor consisting of two micromachined cantilevers (a sensing/reference pair) that is suitable for detection of chemical and biological species. The sensing strategy involves coating the sensing cantilever with receptors that have high affinities for the analyte. The presence of analyte is detected by determining the differential surface stress associated with its adsorption/absorption to the sensing cantilever. An interferometric technique is utilized to measure the differential bending of the sensing cantilever with respect to reference. Surface stress associated with hybridization of single stranded DNA is measured to demonstrate the unique advantages of the sensor.
Copyright Owner
American Institute of Physics
Copyright Date
2008
Language
en
File Format
application/pdf
Recommended Citation
Kang, K.; Nilsen-Hamilton, Marit; and Shrotriya, Pranav, "Differential surface stress sensor for detection of chemical and biological species" (2008). Biochemistry, Biophysics and Molecular Biology Publications. 40.
https://lib.dr.iastate.edu/bbmb_ag_pubs/40
Comments
This is an article from Applied Physics Letters 93 (2008): 143107, doi:10.1063/1.2996411. Posted with permission.