Campus Units
Biochemistry, Biophysics and Molecular Biology
Document Type
Article
Publication Version
Accepted Manuscript
Publication Date
2013
Journal or Book Title
Organic & Biomolecular Chemistry
Volume
11
Issue
44
First Page
7650
Last Page
7652
DOI
10.1039/C3OB41885E
Abstract
Miltiradiene (1), is the precursor of phenolic diterpenoids such as ferruginol (2), requiring aromatization and hydroxylation. While this has been attributed to a single cytochrome P450 (CYP76AH1), characterization of the rosemary ortholog CYP76AH4 led to the discovery that these CYPs simply hydroxylate the facilely oxidized aromatic intermediate abietatriene (3).
Copyright Owner
The Royal Society of Chemistry
Copyright Date
2013
Language
en
File Format
application/pdf
Recommended Citation
Zi, Jiachen and Peters, Reuben J., "Characterization of CYP76AH4 clarifies phenolic diterpenoid biosynthesis in the Lamiaceae" (2013). Biochemistry, Biophysics and Molecular Biology Publications. 86.
https://lib.dr.iastate.edu/bbmb_ag_pubs/86
Comments
This is a manuscript of an article published as Zi, Jiachen, and Reuben J. Peters. "Characterization of CYP76AH4 clarifies phenolic diterpenoid biosynthesis in the Lamiaceae." Organic & biomolecular chemistry 11, no. 44 (2013): 7650-7652. doi: 10.1039/C3OB41885E. Posted with permission.