Theses/Dissertations from 2020
In vitro study of the distinct stages in SNARE-mediated vesicle fusion, Ryan Khounlo
Understanding the structure-function relationship of Class II Diterpene Cyclases, Cody Lemke
Molecular mechanisms of Pyk2 regulation, Hanna S. Loving
Multi-scale computational studies of heterochromatin protein-1, Jazelli Lenae Mueterthies
Characterizing the specificity and nicking activity of CRISPR endonucleases, Cas9 and Cas12a, Karthik Murugan
Developing tools to study the clustering-based activation mechanisms of proline-rich tyrosine kinase 2, Shivani Sharma
Preparation and characterization of recombinant plant chitinases, Samuel Oluwatoyin Shobade
The molecular mechanisms of the bacteriophage T4-Mre11/Rad50 (gp46/gp47) DNA repair complex, Tibebe Antonios Teklemariam
Nutrigenomics and aging: A transcriptomic perspective, Joe Lawrence Webb
Theses/Dissertations from 2019
Application of mass spectrometric technologies to decipher high spatial resolution insights into plant metabolism, Liza Esther Alexander
Ectopic expression of the Arabidopsis homomeric acetyl-CoA carboxylase, Troy Matthew Bunch
Integrated ‘omics’ characterization of conserved nectar production mechanisms using floral and extrafloral eudicot nectaries, Elizabeth Claire Chatt
Characterization of Lamp1 in Drosophila melanogaster, Norin Yasin Chaudhry
Compartment-specific metabolism associated with acetyl-CoA and acyl carrier protein, Xinyu Fu
Insights into the native function of α-synuclein, Brenden James Douglas Hawk
Analysis and characterization of the choline-utilizing microcompartment in uropathogenic E. coli 536, Taylor Irene Herring
Structure and kinetic characterization of plasmodium falciparum apicoplast DNA polymerase (apPOL), Supreet Kaur
Conformational change upon phosphorylation at S713 site of Disrupted-in-schizophrenia-1 (DISC1) leads to a change in the oligomeric state, Luan Minh Nguyen
Donor-and site-specific N-glycosylation analysis of human Fc γ Receptor IIIA from primary natural killer cell, Kashyap Rajeshbhai Patel
Elucidating the role of N-glycosylation in the interaction between Fc γ Receptors (FcγRs) and Immunoglobulin G (IgG) through characterization of endogenous FcγR N-glycosylation and FcγRIII (CD16) binding, Jacob Timothy Roberts
Regulation of acetyl-CoA metabolism in plants: Role of acetyl-CoA synthetase and sirtuin proteins, Naazneen Sofeo
Dynamics of the SNARE-mediated synaptic vesicle fusion pore, Andrew Louis Wiese
Theses/Dissertations from 2018
Structure and function of Xyloglucan Xylosyltransferases, Alan Culbertson
Effects of flanking DNA and a transcriptional activator on the histone acetyltransferase activity of the SAGA complex, Sannie J. Culbertson
Exploring RNA interference in the agricultural pests western corn rootworm, fall armyworm, and southern green stink bug, Courtney Anne Davis-Vogel
Exploring RNA interference in the agricultural pests western corn rootworm, fall armyworm, and southern green stink bug, Courtney Anne Davis-Vogel
Elucidating how N-glycosylation impacts immunoglobulin G Fc structure and receptor binding, Daniel Falconer
The role of allostery in nNOS and SynGAP activity, Quinlin Hanson
Using evolutionary covariance to infer protein sequence-structure relationships, Kejue Jia
Investigating the functional coupling between Rad50 ATP active sites, Katherine Johnson
Characterization of CRISPR RNA guided immunity in Bacillus halodurans type I-C system, Hayun Lee
Protein sequence-structure-dynamics-function relationships: The close association of dynamics with protein function, Sambit Kumar Mishra
Point mutational examination of eukaryotic initiation factor 4E (eIF4E), inclusion bodies analysis, and Barley Yellow Dwarf Virus (BYDV) exonuclease resistant RNA structure mapping and prediction, Melissa Kathryn Sheber
Role of non-catalytic subunits in biotin-dependent carboxylases, Kiran Kumar Shivaiah
Single-molecule FRET investigation of SNARE-mediated exocytosis regulation, Linxiang Yin
Theses/Dissertations from 2017
Phytoglobin as catalytic enzyme for production of ammonia from hydroxylamine and hydrazine, Jagannathan Alagurajan
Methanobactin: Metal binding properties, physiological function and biosynthesis, Bipin Sharma Baral
Investigation of rice diterpenoid phytoalexin biosynthesis, Benjamin C. Brown
Elucidation of regulatory mechanisms of the ITK and its substrate PLCγ1, Sujan Devkota
Investigation of soybean susceptibility to soybean aphids and how aphids affect plant-mediated pest interactions, Jessica Hohenstein
In vitro single vesicle fusion study of Ca2+-triggered SNARE-mediated membrane fusion, Jaewook Kim
Functions of maize genes encoding pyruvate orthophosphate dikinase in developing maize endosperm and their enzymatic properties, Ryan R. Lappe
An enzymology and structural biology approach towards elucidation of E. coli fatty acid biosynthesis and its application to the production of bio-renewables, Aaron Michael Marcella
Gibberellin biosynthesis by bacteria and its effect on the rhizobia-legume symbiosis, Ryan Stephan Nett
A study of cell wall integrity control in transgenic plants expressing polysaccharide-modifying enzymes, Nathan T. Reem
Selection of functional RNA aptamers against Ebola glycoproteins, Shambhavi Shubham
CRISPR-mediated adaptive immune system in E. coli, Chaoyou Xue
Theses/Dissertations from 2016
The idenification of the GLOSSY1-Like gene family and their involvement in Zea mays surface lipid production, Jennifer Chmielowski
Exploring the genetic redundancy of Zea mays fatty acid elongase (FAE), Kayla S. Flyckt
Solid phase synthesis strategies for generating novel chromatin model systems, Margaret K. Gannon
Substrate promiscuity and functional plasticity investigations of class I diterpene synthases, Meirong Jia
Computational Study on the Protein Conformational Transitions and Their Pathways, Jie Liu
Structure and function of the Plasmodium falciparum apicoplast DNA polymerase: the first look at an "atypical" A-family polymerase and its potential in antimalarial drug discovery, Morgan Eilise Milton
Autophagy- and RNS2-mediated mechanism of ribosomal RNA degradation in Arabidopsis thaliana, Stephanie C. Morriss
Exploring genetic-based metabolic and morphological diversity of Arabidopsis thaliana ecotypes influenced by the environment, Jennifer R. Robinson
Knowledge-based approaches for understanding structure-dynamics-function relationship in proteins, Kannan Sankar
Functional characterization of dASCIZ in gene expression and development in Drosophila melanogaster, Saheli Sengupta
Amylolysis of eight different starches with four different species of alpha-amylase, Robert Leonard Sheets
Electron transfer and redox chemistry in hexa-coordinate hemoglobins, Navjot Singh
Comparative kinetic analysis of anaerobic nitrite metabolism in phytoglobins, Ashley Rose Spooner
Role of Non-catalytic Ligands in Macromolecule Function, Muneaki Watanabe
Introducing multiple sites of acetylation to histone H3 via nonsense suppression, Isaac Young
Investigation of SNARE mediated membrane fusion and its regulation by optimized single molecule method, Yicheng Zhu
Theses/Dissertations from 2015
Structural mechanisms of bacterial multidrug efflux pumps, their regulation, and implications for future research in silico, Sylvia Vu Do
Functional analysis of the propanediol utilization microcompartment shell proteins PduB and PduB' in Salmonella enterica, Brent Lehman
Investigating the roles of diterpenoids in rice-Xanthomonas oryzae interactions, Xuan Lu
Investigating the role of chromatin structure in modulating SAGA mediated nucleosomal acetylation, Chitvan Mittal
Understanding the BASEs for catalysis in class II diterpene cyclases results in novel product chemistries, Kevin Charles Potter
Fermentative production of short-chain fatty acids and methyl ketones in Escherichia coli, Alexandra Rachel Volker
Theses/Dissertations from 2014
Isolation and binding properties of methanobactin from the facultative methanotroph Methylocystis strain SB2, Nathan Bandow
Characterization of Ebola virus VP35 first basic patch as a therapeutic target, Jennifer Binning
New insights into the functional organization of xyloglucan biosynthetic enzymes and their catalytic mechanism, Yi-Hsiang Chou
Enzymatic components and physiological roles of mitochondrial fatty acid biosynthesis in plants, Xin Guan
The role of the Immunoglobulin G1 Fc N-glycan in FcγRIIIa affinity, Quinlin Hanson
Role of the PduL enzyme in the function of primitive bacterial organelles found in Salmonella, Yu Liu
Aptamer sensors for live-cell imaging of Pol II promoter activity, Judhajeet Ray
Characterization of RNase X25 and Lamp1 in Drosophila melanogaster, Ayesha Riaz
Investigation of SNARE-mediated exocytosis controlled by synaptic regulatory proteins, Jaeil Shin
Metabolomics based gene function annotation in Escherichia coli and Methanosarcina acetivorans with genetic gain- or loss-of-function strains, Lucas John Showman
A single molecular study of the regulation of SNARE-mediated membrane fusion, Jaekyun Song
Biochemical characterization of the biotin-dependent carboxylases, acetyl-CoA carboxylase and 3-methylcrotonyl-CoA carboxylase, Bryon A. Upton
Epigenetic interplay between histone H3K9me2 and JIL-1 mediated histone H3S10ph, Chao Wang
Function of class one nonsymbiotic plant hemoglobins, Xiaoguang Wang
Fidelity, mismatch extension, and proofreading measurements of apPOL, the Plasmodium falciparum apicoplast-targeted DNA polymerase, Bentley Wingert
Theses/Dissertations from 2013
Molecular regulation of IL-2 inducible T-cell kinase (Itk) and the Tec kinases: A combined experimental and computational study, with emphasis on the N-terminal Pleckstrin Homology domain, Scott Edward Boyken
Optimization of methods for culturing Mycobacterium avium subsp. paratuberculosis from bovine milk and colostrum and application to samples collected from naturally infected dairy cows, Laura Kaitlan Bradner
Wax ester biosynthetic pathway, Daolin Cheng