Biomedical Sciences, Veterinary Clinical Sciences
Journal or Book Title
CPT: Pharmacometrics & Systems Pharmacology
There is growing concern about the limitations of rodent models with regard to recapitulation of human disease pathogenesis. Computational modeling of data from humans and animals sharing similar diseases provides an opportunity for parallel drug development in human and veterinary medicine. This “reverse translational” approach needs to be supported by continuing efforts to refine the in silico tools that allow extrapolation of results between species.
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License
Schneider, Benjamin; Balbas-Martinez, Violeta; Jergens, Albert E.; Troconiz, Inaki F.; Allenspach, Karin; and Mochel, Jonathan P., "Model-Based Reverse Translation Between Veterinary and Human Medicine: The One Health Initiative" (2017). Biomedical Sciences Publications. 48.
Comparative and Laboratory Animal Medicine Commons, Diseases Commons, Veterinary Pathology and Pathobiology Commons, Veterinary Preventive Medicine, Epidemiology, and Public Health Commons, Veterinary Toxicology and Pharmacology Commons