Title
Model-Based Reverse Translation Between Veterinary and Human Medicine: The One Health Initiative
Campus Units
Biomedical Sciences, Veterinary Clinical Sciences
Document Type
Article
Publication Version
Published Version
Publication Date
2017
Journal or Book Title
CPT: Pharmacometrics & Systems Pharmacology
DOI
10.1002/psp4.12262
Abstract
There is growing concern about the limitations of rodent models with regard to recapitulation of human disease pathogenesis. Computational modeling of data from humans and animals sharing similar diseases provides an opportunity for parallel drug development in human and veterinary medicine. This “reverse translational” approach needs to be supported by continuing efforts to refine the in silico tools that allow extrapolation of results between species.
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License
Copyright Owner
The Authors
Copyright Date
2017
Language
en
File Format
application/pdf
Recommended Citation
Schneider, Benjamin; Balbas-Martinez, Violeta; Jergens, Albert E.; Troconiz, Inaki F.; Allenspach, Karin; and Mochel, Jonathan P., "Model-Based Reverse Translation Between Veterinary and Human Medicine: The One Health Initiative" (2017). Biomedical Sciences Publications. 48.
https://lib.dr.iastate.edu/bms_pubs/48
Included in
Comparative and Laboratory Animal Medicine Commons, Diseases Commons, Veterinary Pathology and Pathobiology Commons, Veterinary Preventive Medicine, Epidemiology, and Public Health Commons, Veterinary Toxicology and Pharmacology Commons
Comments
This article is published as Schneider, Benjamin, Violeta Balbas‐Martinez, Albert E. Jergens, Inaki F. Troconiz, Karin Allenspach, and Jonathan P. Mochel. "Model‐Based Reverse Translation Between Veterinary and Human Medicine: The One Health Initiative." CPT: pharmacometrics & systems pharmacology (2017). doi: 10.1002/psp4.12262. Posted with permission.