Campus Units

Biomedical Sciences, Veterinary Clinical Sciences

Document Type

Article

Publication Version

Published Version

Publication Date

2017

Journal or Book Title

CPT: Pharmacometrics & Systems Pharmacology

DOI

10.1002/psp4.12262

Abstract

There is growing concern about the limitations of rodent models with regard to recapitulation of human disease pathogenesis. Computational modeling of data from humans and animals sharing similar diseases provides an opportunity for parallel drug development in human and veterinary medicine. This “reverse translational” approach needs to be supported by continuing efforts to refine the in silico tools that allow extrapolation of results between species.

Comments

This article is published as Schneider, Benjamin, Violeta Balbas‐Martinez, Albert E. Jergens, Inaki F. Troconiz, Karin Allenspach, and Jonathan P. Mochel. "Model‐Based Reverse Translation Between Veterinary and Human Medicine: The One Health Initiative." CPT: pharmacometrics & systems pharmacology (2017). doi: 10.1002/psp4.12262. Posted with permission.

Creative Commons License

Creative Commons Attribution-Noncommercial 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License

Copyright Owner

The Authors

Language

en

File Format

application/pdf

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