Campus Units

Biomedical Sciences, Veterinary Diagnostic and Production Animal Medicine

Document Type

Article

Publication Version

Submitted Manuscript

Publication Date

2019

Journal or Book Title

Preprints

DOI

10.20944/preprints201903.0082.v1

Abstract

Congestive heart failure (CHF) is a major cause of morbidity and mortality with an increasing prevalence in human and canine populations. Similar to humans, overactivation of the renin-angiotensin aldosterone system is involved in the pathophysiology of CHF in dogs. Current therapeutic strategies for the management of canine CHF include the use of RAAS inhibitors, diuretics and inodilators. The present review summarizes data from our own research on the modulation of the renin-angiotensin cascade in dogs in dogs, together with new findings (including novel therapeutic targets) from the veterinary and the human literature.

Comments

This is a pre-print of the article Mochel, Jonathan. "A Review of Relevant Therapeutic Targets for the Management of Congestive Heart Failure in Dogs: Present and Future Directions." Preprints (2019). DOI: 10.20944/preprints201903.0082.v1. Posted with permission.

Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

Copyright Owner

The Author

Language

en

File Format

application/pdf

Published Version

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