Document Type

Letter to the Editor

Publication Version

Published Version

Publication Date

1996

Journal or Book Title

Nature Genetics

Volume

14

First Page

380

Last Page

382

DOI

10.1038/ng1296-380

Abstract

Closely related (confamilial) genera often retain large chromosomal tracts in which gene order is colinear, punctuated by structural mutations such as inversions and translocations 1. To explore the possibility that conservation of gene order might extrapolate to more distantly related taxa, we first estimated an average structural mutation rate. Nine pairs of taxa, for which there exist both comparative genetic maps and plausible estimates of divergence time, showed an average of0.14 (±0.06) structural mutations per chromosome per million years of divergence (Myr; Table 1). This value is offered as a first approximation, acknowledging that refined comparative data and/or divergence estimates may impel revision.

Comments

This letter is from Nature Genetics 14 (1996): 380, doi:10.1038/ng1296-380.

Rights

Works produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted.

Language

en

File Format

application/pdf

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