Campus Units

Chemical and Biological Engineering, Genetics, Development and Cell Biology, Electrical and Computer Engineering, Materials Science and Engineering, Ames Laboratory

Document Type

Conference Proceeding

Conference

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)

Publication Version

Accepted Manuscript

Link to Published Version

https://doi.org/10.1109/NANO.2017.8117495

Publication Date

2017

Journal or Book Title

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)

First Page

1056

Last Page

1059

Research Focus Area

Health Care Technology and Biomedical Engineering, Advanced and Nanostructured Materials

DOI

10.1109/NANO.2017.8117495

Conference Title

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)

Conference Date

July 25-28, 2017

City

Pittsburgh, PA

Abstract

This paper reports the behaviors of neuron cell N27 growth on nanostructured surface and under transcranial magnetic stimulation (TMS) at single cell level for the first time. First, the growth of neuron cell N27 on anodic aluminum oxide (AAO) nanoporous surface has been studied. It has been found the cells show much preference to grow on the nanostructured surface over the flat coverslip glass surface. Second, the sizes of cells grown on AAO nanoporous surface with TMS and without TMS have been studied. It has been found the sizes of cells with TMS are statistically smaller than those without TMS in the same period of time, indicating the TMS might speed up the cell division. To verify this observation, the growth of single N27 cells inside SU8 microholders with and without TMS has been investigated. It has been found that up to 17% more daughter cells can be divided when the cells are subjected to TMS compared to those without TMS. All these results suggest the TMS can contribute to the growth of N27 cells, benefiting the neuron regeneration.

Comments

This is a manuscript of a proceeding published as Che, Xiangchen, Joseph Boldrey, Xiaojing Zhong, Ian Schneider, David Jiles, and Long Que. "Studies of single neuron cell growth on nanoporous surface and under transcranial magnetic stimulation." In 2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO) (2017): 1056-1059. DOI: 10.1109/NANO.2017.8117495. Posted with permission.

Rights

© 2017 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.

Copyright Owner

IEEE

Language

en

File Format

application/pdf

Published Version

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Article Location

 
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